experience
Tony's professional and research experience.
Work Experience
Transcripta Bio Palo Alto, CA
Machine Learning Consultant (Part-Time) Sep 2023 - Dec 2024
- Leading experiments on generative models for molecules with desired gene expression, resulting in the discovery of several novel molecules with better predicted bioactivity profile.
- Enabling company’s first ML-based virtual screening pipeline with compound library standardization, characterization and featurization - which resulted in several wet-lab validated hits.
Recursion Salt Lake City, UT
Software Engineer (Part-Time) Sep - Dec 2022
Software Engineering Intern Jun - Sep 2022
- Implemented gene search and enrichment analysis of biological pathways with React and Python using known biology databases to accelerate drug-target discovery workflow. Setup SLO alerts using OpenTelemetry and Prometheus.
- Built full-stack graph visualization and analysis app for millions of relationships between biological entities using Dash.
Amgen Burnaby, BC
Bioinformatics Co-op Jan - Apr 2022
- Developed binding affinity prediction model of antibody and target protein on cell sorting data using PyTorch and ESM.
- Built Dash web app to visualize immune repertoire containing thousands of sequences through network graph.
Google Waterloo, ON
Software Developer Intern May - Aug 2021
- Introduced contrastive learning to Retail AI ranking model and reduced average first click position by 0.36 using TensorFlow.
- Implemented adaptive multi-objective loss balancing algorithms (GradNorm, Uncertainty Weighting) to reduce over-fitting in multi-task ranking model.
- Used C++ and Flume (Apache Beam) to build metric aggregation pipelines that processed terabytes of search logs to provide insights on search quality.
Georgian Toronto, ON
Machine Learning Engineering Intern Sep - Dec 2020
- Built ML Platform command line tool that enables data scientists to seamlessly train hundreds of dockerized reproducible experiments on cloud in one command.
- Trained and evaluated models predicting startups’ raise likelihood to help investment team on candidates prioritization.
- Generated novel features from large news dataset using Apache Spark and increased AUPR by 10% compared to baseline.
Google Waterloo, ON
STEP Intern May - Aug 2020
- Proposed and implemented a full stack web & mobile platform that enables non-technical users to create functional bots.
- Owned and developed Flutter/Dart application and Cloud Firestore component. Proposed and communicated key technical designs in schema and framework choice, resulting in accelerated completion of cross-platform app.
- 20% Project: Worked with Cloud Health team to generate human mutation histogram, using SQL and Python to pull data from Genome Aggregation Database in BigQuery.
Research Experience
Northeastern University / Broad Institute of MIT and Harvard Boston, MA
Visiting researcher Feb 2025 - Present
- Research: Foundation model for bio-molecular generation, and antibiotics discovery applications.
- Supervisor: Dr. Wengong Jin
Simon Fraser University Burnaby, BC
PhD in Computing Science May 2023 - Present
- Research: Structure-based drug design with generative flow networks and flow matching models.
- Supervisor: Dr. Martin Ester
Communications
Guest interviewer - InterBios Podcast May 2024
Interviewed Dr. Anthony Fejes - CEO of HTuO Biosciences on the role of molecular simulation on drug discovery.
Guest writer - Valence Portal Blogs Apr 2024
Published article on AI for Drug Design and Generative Flow Networks (link)
Supervising
Grayson Lee Oct 2023 - May 2024
Geometric-informed GFlowNets for Structure-Based Drug Design - MoML 2024 (Spotlight)
Academic Service
Reviewer
Transactions on Machine Learning Research (TMLR) Oct 2024 -